Genetics
Genetics
DNA bond strength (nucleotides)
“Crazy Glue”:
Strongest bonds are between Cytosine and Guanine, strong like Crazy Glue (3 H-bonds), whereas the A=T only have 2 H-bonds.
This is relevant to DNA replication, as the weaker A=T will be the site whereRNA primer
Mitochondrial DNA (mt
“mt
mt
Maternal Transfer
Mutates Tremendously (high mutation rate)
tRNA
Fortunately, tRNA
Pyrimidines are CUT from purines
Pyrimidines are Cytosine, Uracil, Thiamine and are one ring structures.
Purines are double ring structures.
Dicarboxylic acids (alpha, omega) from C2-C10
“Crazy Glue”:
Strongest bonds are between Cytosine and Guanine, strong like Crazy Glue (3 H-bonds), whereas the A=T only have 2 H-bonds.
This is relevant to DNA replication, as the weaker A=T will be the site where
Mitochondrial DNA (
“
Maternal Transfer
Mutates Tremendously (high mutation rate)
Fortunately, t
Pyrimidines are CUT from purines
Pyrimidines are Cytosine, Uracil, Thiamine and are one ring structures.
Purines are double ring structures.
"Oh My, Such Good Apple Pie, Sweet As Sugar"
oxalic, malonic, succinic, glutaric, adipic, pimelic, suberic, azelaic, sebacic
oxalic, malonic, succinic, glutaric, adipic, pimelic, suberic, azelaic, sebacic
Molecular Genetics
"EXons EXpressed, INtrons IN the trash"
DNA expression into maturemRNA
DNA expression into mature
Pyrimidines are "CUT" from purines.
Pyrimidines are Cytosine, Uracil, Thiamine and are one ring structures. Purines are double ring structures.
Pyrimidines are Cytosine, Uracil, Thiamine and are one ring structures. Purines are double ring structures.
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