Protein
Protein
Catabolism steps of branched chain amino acids
“Truck hit the Ox to Death”:
Essential amino acids
PVT. TIM HALL:
is short for Private in the military.
Arg and His are considered semiessential .
Alternatively: “MATT VIL PHLy”.
Essential amino acids
“PVT. TIM HALL always argues, never tires”:
‘Never tires': T is not Tyr, but is bothThr and Trp.
Fasting state: branched-chain amino acids used by skeletal muscles
“Muscles LIVe fast”:
AcetylCoA and acetacetylCoA : amino acids forming them
“A Lighter Lease” (A LyTr LeIs):
: creatinine elevation: causes
ABCD:
“Nice GAMs!”:
Gam is slang for a person’s leg, especiallay an attractive female’s leg: “Nice gams = nice legs!”
Creatine phosphate is amuscle energy store, and spontaneously converts to creatinine which is excreted in the urine in direct proportion to muscle mass: clinically useful, such as in MS Dx.
Nitric oxide: amino acid precursor
When the dentist works on your teeth, you say, “AAArg! (Arginine )” before he administersNitric Oxide (NO) to take the pain away.
Other players necessary for NO synthesis: NOsynthase , Ca++, NADPH.
Urea Cycle
Ordinarily, Careless Crappers, Are Also Frivolous About Urination.
“Truck hit the Ox to Death”:
- Tr
ansamination - Oxidative decarboxylation
- De
hydrogenation
Essential amino acids
PVT. TIM HALL:
- P
he - Val
- T
hr - T
rp - I
le - Met
- His
- A
rg - Leu
- L
ys
Alternatively: “MATT VIL PHLy”.
Essential amino acids
“PVT. TIM HALL always argues, never tires”:
- P
he - Val
- T
hr - T
rp - I
le - Met
- His
- A
rg - Lue
- L
ys
‘Never tires': T is not Tyr, but is both
Fasting state: branched-chain amino acids used by skeletal muscles
“Muscles LIVe fast”:
- L
eucine - I
soleucine - V
aline
“A Lighter Lease” (A LyTr LeIs):
- A=AcetylCoA or Acetoacetyl CoA
- Ly=Lysine
- Tr=Tryptophan
- Le=Leucine
- Is=Isoleucine
ABCD:
- A
zotremia (pre-renal) - Bleeding (GI)
- Catabolic status
- Diet (high protein parenteral nutrition)
“Nice GAMs!”:
- G
lycine - A
rginine - Methionine
Creatine phosphate is a
Nitric oxide: amino acid precursor
When the dentist works on your teeth, you say, “AAArg! (
Other players necessary for NO synthesis: NO
Urea Cycle
Ordinarily, Careless Crappers, Are Also Frivolous About Urination.
- O
rnithine - C
arbamoyl - C
itrulline - A
rginosuccinate - A
spartate - F
umarate - A
rginine - Urea
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